Publications

(2015 ~ 현재)

2026

(Accepted) Ethionamide Preconditioning Enhances the Therapeutic Efficacy of Human Mesenchymal Stromal Cells in an Alzheimer's Disease Model

Stem Cell Research & Therapy

Hyo Jin Son, Na-Hee Lee, Hyeongseop Kim, Su Hyeon Myeong, Ji Hyeon Kang, Na Kyung Lee, Seung-yeon Lee, Hyemin Jang, Sang Won Seo, Jong Wook Chang, Duk L. Na and Hee Jin Kim

2026

Document

Identification of non-toxic AAV capsid variants with enhanced deep retinal transduction and extended distribution following subretinal delivery

Biochemical and Biophysical Research Communications

Lim H, Choi SH, Jeon YE, Park HW, Choi YK, Muthukumar Elangovan, Lee NK, Kwon SJ, Chang JW

2026

Document

Exploring the Potential of Wharton's Jelly-Derived Mesenchymal Stem Cells as a Therapeutic Approach for Preterm Premature Rupture of Membranes

International Journal of Stem Cells

Kim HS, Kim HJ, Jeon SY, Oh SY, Park SE, Jeon HB, Kim JS, Chang JW, Choi SJ

2026

Document

Intracerebroventricular Human Mesenchymal Stem Cells Induce MMP9-driven transient Inflammation in Alzheimer’s Disease

Stem Cell Research and Therapy

Myeong SH, Lee NK, Lee NH, Choi SJ, Son HJ, Chang JW, Kim HJ, Na DL

2025

Document

Evaluation of AAV transduction efficiency via multiple delivery routes: Insights from peripheral and central nervous system analysis

Neuroscience

Lee NK, Na DL, Kim JW, Lee BW, Kim HJ, Jang HM, Lee JH, Chang JW

2025

Document

Prolonged Chronic Cerebral Hypoperfusion Dose Not Exacerbate Tau Pathology in a Tauopathy Mouse Model

Journal of Integrative Neuroscience

Lee NK, Na DL, Kim HJ, Jang HM, Sa JK, Ko BS, Chang JW

2024

Document

Synergistic effect of Wharton's jelly-derived mesenchymal stem cells and insulin on Schwann cell proliferation in Charcot-Marie-Tooth disease type 1A treatment

Neurobiology of Disease

Oh SJ, Kim HS, Park SE, Kim JH, Kim YJ, Choi SJ, Oh SY, Jeon HB, Chang JW

2024

Document

Safety and tolerability of Wharton's jelly-derived mesenchymal stem cells in patients with Duchenne muscular dystrophy: a phase 1 clinical study

Journal of Clinical Neurology

Lee JW, Park SE, Kim MR, Kim HS, Kwon JY, Jeon HB, Chang JW, Lee JH

2024

Document

Anti-necroptic effects of human Wharton's jelly-derived mesenchymal stem cells in skeletal muscle cell death model via secretion of GRO-a

PLoS One

Park SE, Kwon SJ, Kim SJ, Jeong JB, Kim MJ, Choi SJ, Oh SY, Ryu GH, Chang JW, Jeon HB

2024

Document

Application of Deep Neural Networks in the manufacturing process of Mesenchymal Stem Cells Theapeutics

International Journal of Stem Cells

Ngo D, Lee J, Kwon SJ, Park JH, Cho BH, Chang JW

2024

Document

Nervonic acid improves fat transplantation by promoting adipogenesis and angiogenesis

International Journal of Molecular Medicine

Song JH, Kim SJ, Kwon S, Jeon SY, Park SE, Choi SJ, Oh SY, Jeon HB, Chang JW

2024

Document

Glutaminase-1 Inhibition Alleviates Senescence of Wharton’s Jelly-derived Mesenchymal Stem Cells via Senolysis

Stem Cells Translational Medicine

Lee EJ, Kim SJ, Jeon SY, Chung SB, Park SE, Kim JS, Choi SJ, Oh SY, Ryu GH, Jeon HB, Chang JW

2024

Document

(Review) Manufacturing Cell and Gene Therapies: Challenges in Clinical Translation

Annals of Laboratory Medicine

Lee NK, Chang JW

2023

Document

Nervonic Acid Inhibits Replicative Senescence of Human Wharton’s Jelly-Derived Mesenchymal Stem Cells

International Journal of Stem Cells

Kim SJ, Kwon SJ, Chung SB, Lee EJ, Park SE, Choi SJ, Oh SY, Ryu GH, Jeon HB, Chang JW

2023

Document

Iron Oxide Nanoparticle-Incorporated Mesenchymal Stem Cells for Alzheimer's Disease Treatment

Nano Letters

Jung MG, Kim HS, Hwang JW, Choi YJ, Kang MK, Kim CS, Hong JH, Lee NK, Moon SJ, Chang JW, Choi SJ, Oh SY, Jang HM,

Na DL, Kim BS

2022

Document

A New Method of Myostatin Inhibition in Mice via Oral Administration of Lactobacillus casei Expressing Modified Myostatin Protein, BLS-M22

International Journal of Molecular Sciences

Sung DK, Kim HS, Park SE, Lee JW,Kim JA, Park YC, Jeon HB, Chang JW, Lee JH

2022

Document

Combination of Dexamethasone and Tofacitinib Reduces Xenogeneic MSC-Induced Immune Responses in a Mouse Model of Alzheimer's Disease

Biomedicines

Lee NK, Myeong SH, Hwang JW, Sa JK, Son HJ, Kim HJ, Jang HM, Chang JW, Na DL

2022

Document

Wharton’s Jelly-Derived Mesenchymal Stem Cells with High Aurora Kinase A Expression Show Improved Proliferation, Migration, and Therapeutic Potential

Stem Cells International

Kim SJ, Park SE, Jeong JB, Oh SJ, Choi A, Kim YH, Choi SJ, Oh SY, Ryu GH, Jeon HB, Chang JW

2021

Document

Wharton’s Jelly-Derived Mesenchymal Stem Cells Reduce Fibrosis in a Mouse Model of Duchenne Muscular Dystrophy by Upregulating MicroRNA 499

Biomedicines

Park SE, Jeong JB, Oh SJ, Kim SJ, Kim HS, Choi A, Choi SJ, Oh SY, Ryu GH, Lee JH, Jeon HB, Chang JW

2021

Document

Immunosuppressant Drugs Mitigate Immune Responses Generated by Human Mesenchymal Stem Cells Transplanted into the Mouse Parenchyma

Cell Transplantation

Hwang JW, Myeong SH, Lee NH, Kim HS, Son HJ, Chang JW, Lee NK, Na DL

2021

Document

Exposure of Mesenchymal Stem Cells to an Alzheimer’s Disease Environment Enhances Therapeutic Effects

Stem Cells International

Park SE, Kim HS, Kwon SJ, Kim MJ, Choi SJ, Oh SY, Ryu GH, Jeon HB, Na DL, Chang JW

2021

Document

Intraspinal Cavity Injection of Human Mesenchymal Stem Cells and Tracking their Migration into the Rat Brain

JoVE

Kim HS, Lee S, Chang JW, Kim AR, Jang H, Na DL

2021

Document

Comparative Proteomic Analysis of the Mesenchymal Stem Cells Secretome from Adipose, Bone Marrow, Placenta and Wharton's Jelly

International Journal of Molecular Sciences

Shin SH, Lee JM, Kwon YM, Park KS, Jeong JH, Choi SJ, Bang SI, Chang JW, Lee CJ

2020

Document

Fibulin 5, a human Wharton's jelly‐derived mesenchymal stem cells‐secreted paracrine factor, attenuates peripheral nervous system myelination defects through the Integrin‐RAC1 signaling axis

STEM CELLS

Won SY, Kwon SJ, Jeong HS, Chung KW, Choi BO, Chang JW, Lee JE

2020

Document

Pressure Stimuli Improve the Proliferation of Wharton's Jelly-Derived Mesenchymal Stem Cells under Hypoxic Culture Conditions

International Journal of Molecular Sciences

Park SE, Kim HS, Kwon SJ, Choi SJ, Oh SY, Ryu GH, Jeon HB, Chang JW

2020

Document

Ethionamide Preconditioning Enhances the Proliferation and Migration of Human Wharton's Jelly-Derived Mesenchymal Stem Cells

International Journal of Molecular Sciences

Lee NH, Myeong SH, Son HJ, Hwang JW, Lee NK, Chang JW, Na DL

2020

Document

Anti-Fibrotic Effect of Human Wharton’s Jelly-Derived Mesenchymal Stem Cells on Skeletal Muscle Cells, Mediated by Secretion of MMP-1

International Journal of Molecular Sciences

Choi A, Park SE, Jeong JB, Choi SJ, Oh SY, Ryu GH, Lee JH, Jeon HB, Chang JW

2020

Document

Exploring the Potential of Mesenchymal Stem Cell-Based Therapy in Mouse Models of Vascular Cognitive Impairment

International Journal of Molecular Sciences

Lee NK, Kim HS, Chang JW, Jang HM, Kim HN, Yang JH, Kim JY, Son JP, Na DL

2020

Document

A Comparison of Immune Responses Exerted Following Syngeneic, Allogeneic, and Xenogeneic Transplantation of Mesenchymal Stem Cells into the Mouse Brain

International Journal of Molecular Sciences

Hwang JW, Lee NK, Yang J, Son HJ, Bang SI, Chang JW, Na DL

2020

Document

Recovery of Tendon Characteristics by Inhibition of Aberrant Differentiation of Tendon Derived Stem Cells from Degenerative Tendinopathy

International Journal of Molecular Sciences

Kim SJ, Oh HW, Chang JW, Kim SJ

2019

Document

Cerebrospinal fluid from Alzheimer’s disease patients as an optimal formulation for therapeutic application of mesenchymal stem cells in Alzheimer’s disease

Scientific Reports

Lee J, Kwon SJ, Kim JH, Jang H, Lee NK, Hwang JW, Kim JH, Chang JW, Na DL

2018

Document

(Review) Killing two birds with one stone: The multifunctional roles of mesenchymal stem cells in the treatment of neurodegenerative and muscle diseases

Histology and Histopathology

Lee NK, Na DL, Chang JW

2018

Document

(Review) Optimal mesenchymal stem cell delivery routes to enhance neurogenesis for the treatment of Alzheimer's disease: optimal MSCs delivery routes for the treatment of AD

Histology and Histopathology

Park SE, Lee NK, Na DL, Chang JW

2017

Document

Lowering the concentration affects the migration and viability of intracerebroventricular-delivered human mesenchymal stem cells

Biochemical and Biophysical Research Communications

Kim HS, Lee NK, Yoo D, Lee J, Choi SJ, Oh W, Chang JW, Na DL

2017

Document

Agouti Related Peptide Secreted Via Human Mesenchymal Stem Cells Upregulates Proteasome Activity in an Alzheimer's Disease Model

Scientific Reports

Lee NK, Park SE, Kwon SJ, Shim S, Byeon Y, Kim JH, Na DL, Chang JW

2017

Document

Magnetic Resonance Imaging of Ferumoxytol-Labeled Human Mesenchymal Stem Cells in the Mouse Brain

Stem Cell Reviews and Reports

Lee NK, Kim HS, Yoo D, Hwang JW, Choi SJ, Oh W, Chang JW, Na DL

2016

Document

Distribution of human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) in canines after intracerebroventricular injection

Neurobiology of Aging

Park SE, Jung NY, Lee NK, Lee J, Myeong SH, Kim HS, Suh YL, Lee JI, Cho KR, Chang JW, Na DL

2016

Document

Inhibition of never in mitosis A (NIMA)-related kinase-4 reduces survivin expression and sensitizes cancer cells to TRAIL-induced cell death

Oncotarget.

Park SJ, Jo DS, Jo SY, Shin DW, Shim S, Jo YK, Shin JH, Ha YJ, Chang JW, Kim JC, Cho DH

2016

Document

Activin A secreted by human mesenchymal stem cells induces neuronal development and neurite outgrowth in an in vitro model of Alzheimer's disease: neurogenesis induced by MSCs via activin A

Archives of Pharmacal Research

Park SE, Lee J, Chang EH, Kim JH, Sung JH, Na DL, Chang JW

2016

Document

Anti-apoptotic Effects of Human Wharton's Jelly-derived Mesenchymal Stem Cells on Skeletal Muscle Cells Mediated via Secretion of XCL1

Molecular Therapy

Kwon S, Ki SM, Park SE, Kim MJ, Hyung B, Lee NK, Shim S, Choi BO, Na DL, Lee JE, Chang JW

2016

Document

Intra-Arterially Delivered Mesenchymal Stem Cells Are Not Detected in the Brain Parenchyma in an Alzheimer's Disease Mouse Model

PLoS One

Lee NK, Yang J, Chang EH, Park SE, Lee J, Choi SJ, Oh W, Chang JW, Na DL

2016

Document

Distribution of human umbilical cord blood-derived mesenchymal stem cells in the Alzheimer's disease transgenic mouse after a single intravenous injection.

Neuroreport

Park SE, Lee NK, Lee J, Hwang JW, Choi SJ, Hwang H, Hyung B, Chang JW, Na DL

2015

Document

GDF-15 secreted from human umbilical cord blood mesenchymal stem cells delivered through the cerebrospinal fluid promotes hippocampal neurogenesis and synaptic activity in an Alzheimer's disease model

Stem Cells and Development

Kim DH, Lee D, Chang EH, Kim JH, Kyung JW, Kim SH, Oh JS, Shim SM,Na DL, Oh W, Chang JW

2015

Document

Inhibition of autophagy suppresses sertraline-mediated primary ciliogenesis in retinal pigment epithelium cells

PLoS One

Kim ES, Shin JH, Park SJ, Jo YK, Kim JS, Kang IH, Nam JB, Chung DY, Lee EH, Chang JW, Cho DH